Production of enantiomerically pure D-Phenylglycine using Pseudomonas aeruginosa 10145 as biocatalyst
نویسندگان
چکیده
منابع مشابه
Enantiomerically Pure D-Phenylglycine Production using Immobilized Pseudomonas aeruginosa 10145 in Calcium Alginate Beads
Em trabalhos anteriores em nosso laboratório, uma cepa de Pseudomonas aeruginosa demonstrou ter atividade enzimática na conversão de arilaminonitrilas em D-amino ácidos. Essa atividade enzimática aumentou por indução de modo a produzir D-fenilglicina enantiomericamente pura a partir de 2-fenil-2-aminoacetonitrila. No presente trabalho, as melhores condições para essa transformação são descritas...
متن کاملENANTIOPURE R(-)-3-AMINOISOBUTYRIC ACID SYNTHESIS USING Pseudomonas aeruginosa AS ENANTIOSPECIFIC BIOCATALYST
The main goal of this research was the synthesis of enantiopure R(-)-3-aminoisobutyric acid from dihydrothymine with good yield, high stereospecificity and relative simplicity. Seventy two percent yield of the product was obtained in three steps. Step one consisted of dihydrothymine racemization. Step two was a dihydropyrimidinase reaction involving the Pseudomonas aeruginosa 10145 bacterial st...
متن کاملSynthesis of enantiomerically pure D-FDOC, an anti-HIV agent.
The beta-D-enantiomer of FDOC (2',3'-dideoxy-5-fluoro-oxacytidine) exhibits potent anti-HIV-1 activity. It was obtained in optically pure form by employing a tandem kinetic resolution/chiral salt crystallization protocol. In addition, conditions were developed that allowed the unwanted butyrate ester of the L-enantiomer of FDOC to be racemized. This material could then be recycled in future res...
متن کاملUse of newly isolated phages for control of Pseudomonas aeruginosa PAO1 and ATCC 10145 biofilms.
Pseudomonas aeruginosa is a relevant opportunistic pathogen involved in nosocomial infections that frequently shows low antibiotic susceptibility. One of its virulence factors is associated with the ability to adhere to surfaces and form virulent biofilms. This work describes the isolation and characterization of lytic phages capable of infecting antibiotic-resistant P. aeruginosa strains. In a...
متن کاملEnhancement of Pseudomonas Aeruginosa Growth and Rhamnolipid Production Using Iron-Silica Nanoparticles in Low-Cost Medium
The application of iron-silica (Fe-Si) nanoparticles for the enhancement of the Pseudomonas aeruginosa growth and rhamnolipid production in molasses medium was studied. The experiments were designed based on the response surface method (RSM) to optimize growth and rhamnolipid production. The concentration of nanoparticles and the time required to add nanoparticles to culture medium were conside...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brazilian Journal of Chemical Engineering
سال: 2008
ISSN: 0104-6632
DOI: 10.1590/s0104-66322008000100002